28 August 2008
Editorial:
Antihypertensive treatment: Is anybody old enough to make treatment useless?
By: Alberto Zanchetti
The results of the HYVET trial on the benefits of blood pressure lowering in the very old hypertensive (aged 80 years or older) have recently been published. Alberto Zanchetti provides in-depth discussion of the importance of this trial for the management of hypertension.
28 August 2008
Editorial:
Bivalirudin and fondaparinux – The new parenteral anticoagulants on the block
By: Michel Bertrand
Anticoagulation in acute coronary syndromes or during PCI is a major challenge, because bleeding and clotting have potentially disastrous consequences. Various recent trials have addressed the need to find safer alternatives to standard unfractionated heparin, and in his Editorial, InCirculation.net Editorial Board member Michel Bertrand discusses the particular efficacy and safety of two such powerful anticoagulants, bivalirudin and fondaparinux.
22 August 2008
Editorial:
The ISAR-REACT-3 trial
By: Freek W.A. Verheugt
ISAR-REACT-3 set out to compare the performance of bivalirudin and heparin in patients who were undergoing elective PCI but who were not treated with a GbIIb/IIIa blocker. Freek Verheugt discusses the results of the trial.
